The aim of this study was to formulate an anti acne herbal cream containing various herbs and to compare the efficacy of Piper nigrum and piperine against the Propionibacterium acne and Staphylococcus epidermidis. Three types of creams are formulated namely F1 to F3. All the formulations were evaluated for various parameters like pH, viscosity, acid value, saponification value, irritation and antibacterial activity. The formulation F3 which containing piperine shows highest antibacterial activity.
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